Sjogren's Syndrome

Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

Also Known As:

Sjogren Syndrome; Syndrome, Sicca; Sjogrens Syndrome; Syndrome, Sjogren's; Sicca Syndrome

Musculoskeletal Diseases: 751
- Rheumatic Diseases: 10609
  - Rheumatoid Arthritis: 64385
    - Sjogren's Syndrome: 1450
- Joint Diseases: 6625
  - Arthritis: 34130
    - Rheumatoid Arthritis: 64385
      - Sjogren's Syndrome: 1450
Stomatognathic Diseases: 725
- Mouth Diseases: 98
  - Salivary Gland Diseases: 104
    - Xerostomia: 2723
      - Sjogren's Syndrome: 1450
Eye Diseases: 3620
- Lacrimal Apparatus Diseases: 719
  - Dry Eye Syndromes: 5916
    - Sjogren's Syndrome: 1450
Skin and Connective Tissue Diseases
- Connective Tissue Diseases: 3325
  - Rheumatic Diseases: 10609
    - Rheumatoid Arthritis: 64385
      - Sjogren's Syndrome: 1450
Immune System Diseases: 4430
- Autoimmune Diseases: 35458
  - Rheumatoid Arthritis: 64385
    - Sjogren's Syndrome: 1450

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